There might not necessarily be an audible difference purely based on cable construction so the best thing is to experiment. It is one element in how a cable is constructed, there are many other bits that also count for a lot.
I have solid core copper Audioquest speakers cables and compared with more expensive cables they surprisingly aren't as bad as every other Audioquest product I've bought before I got exposure to more interesting and audio cables with different construction techniques. But I definitely can't tell you how the solid core construction impacts on how these cables sound? They also have solid conductors of different sizes supposedly to optimise different frequencies.
One of the nicest speaker cables I've heard use hollow core copper as a conductor so there are even more variations on this theme, so there is plenty for you to explore. Solid core cables does have other drawbacks, mostly as being difficult to work with (bending and fitting connectors are a pain). At some point I'd love to replace these, but they are not the current bottleneck in my system. The hollow core is nicer in that they are more flexible, but you have to treat them very carefully.
But I can't emphasise this enough, your best bet is to experiment with cables of different construction types, try them in your system and trust you own ears. Even before you get to cables there are a ton of other optimisation to take care of such as your room acoustic space (unless this is for a headphone) and focusing on system component matching. Then when these are all in place, tinkering with cables is a huge amount of fun where every cable swap shows you exactly what it does.
opcorn:
