Yes - in the sense of economy vs. necessity. Higher primary impedance means larger core, more windings (as in higher resistance, increased losses) or both - for what purpose? To go down from 12 Hz - 6 Hz? (One is ignoring the H.T. shenanningans for now; the thread did start off as looking for a replacement for a Leak TL-25.)
Indeed !
But now that you have choosen M6X you can reduce the number of turns or even use a smaller core, just void to go over 1.4 Tesla.
After that (and having "reoptimized" wire gauge to keep both primary and secondary layers full) you will notice some improvement on hi frequency side. But . . .
Interwinding C as per adjacent turns perhaps, total intersection C not (see previous post). We have both already found that too much total intersection-capacitance can start giving us phase shift grief not too comfortably > 30kHz, long before leakage influences start. I also cannot see the relevance of 400+ kHz - perhaps later.
. . . 400Khz is already very (and unnecessary) hi, this value being the theorical f-3 for the specified tube's rp and the obtained leakage inductance.
What we really need is to insure that there is no peaks or dips caused by parasitic caps.
Yes, in the blue window the value shown is the estimated "intersection C" wich usually resonate with Leak L at a frequency indicated by "Fo" in the same window wich is much lower (but not yet objectionable

)
Another cause of peaks and dips if the self resonnant frequency of each primary section.
You can see it by right clicking on each in the "Winding" window at the center.
They all should be at least equal the the "Fo" stated just above and preferably above 100Khz so that "in band" phase shift remains lo enough to allow some feed back without instability.
To acheive that you can reduce the self capacitance of each section by inserting some insulation between their layers.
Enter a value (in mm) in the green box at the right of the "copper" window and right click again on one of the primary section.
Be aware that this reduces the "Max allowed thickness" of the inter winding insulator and also increases the Leak L

Usally you don't need any inter layer insulation in the secondary, remove it setting the corresponding "ILThick" to zero.
Here again some iterations are necessary.
Have fun and best wishes for 2012 to all !
Yves.